The mice’s hematological effect of given the Staphylococcus aureus and Persea americana

نویسندگان

چکیده

Staphylococcus aureus is often the cause of various diseases and food poisoning in animals humans. Avocado seeds ( Persea americana , Mill) contain important compounds that have antimicrobial activity. This study aimed to observe hematological dynamics mice Mus musculus domesticus ) infected with S. induced by P. extract. BALB/c male aged 12 weeks were divided into 6 groups 5 each group, named K-1, K-2, K-3, K-4, K-5, K-6. All 1x10 8 CFU cell/mL intraperitoneally (IP) on day 0. After blood sample was taken, then K-1 given a single dose tetracyclin 130 mg/kg BW, K-2 mg/kb BW oferythromycin, K-3 aquabidest (placebo), K-4 extract 300 K-5 at 600 K-6 1200 BW. The treatment for 7 consecutive days, second taken analyzed VetScan-HM5 analyzer interpreted. It concluded infection caused leukopenia potentially followed lymphopenia, neutrophilia, monocytosis. occurrence microcytosis can lead anemia, which be categorized as microcytic hypochromic or normocytic normochromic. Administration (K-4) days after found effective improving values back normal.

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ژورنال

عنوان ژورنال: BIO web of conferences

سال: 2021

ISSN: ['2273-1709', '2117-4458']

DOI: https://doi.org/10.1051/bioconf/20213306016